11月27日 王育才:Three Dimensional Deformable Biomimetic Heterostructures for Dynamic Biointerfaces


 
报告题目:Three Dimensional Deformable Biomimetic Heterostructures for Dynamic Biointerfaces
时间:11月27日 14:00
报告人:中国科学技术大学 王育才 教授
主持人:程义云 教授
报告地点:闵行生科院534小会议室
 
报告人简介:王育才,轮盘机:教授,博士生导师,中组部“青年千人”计划入选者(2015年)。2005年于中国科学技术大学获得学士学位;2010年于中国科学技术大学获得博士学位;2011年1月起先后于圣路易斯华盛顿大学生物医学工程系、佐治亚理工学院生物医学工程系及芝加哥大学James Franck研究所从事博士后研究。2015年回到中国科学技术大学生命科学学院任教。多年来一直从事纳米材料在癌症治疗及成像领域的研究,在国际学术期刊发表研究论文50余篇,引用次数超过2600次,还为Advanced Functional Materials及Macromolecular Bioscience撰写邀请综述,并为Nature Materials撰写论文评论。
 
报告摘要:Scales are rooted in soft tissues, and are regenerated by specialized cells. The realization of dynamic synthetic analogues with inorganic materials has been a significant challenge, because the abiological regeneration sites that could yield deterministic growth behavior are hard to form. Here we have overcome this fundamental hurdle by constructing a mutable and deformable array of three-dimensional calcite heterostructures that are partially locked in silicone. Individual calcite crystals exhibit asymmetrical dumbbell shapes and are prepared by a parallel tectonic approach under ambient conditions. The silicone matrix immobilizes the epitaxial nucleation sites through self-templated cavities, which enables symmetry breaking in reaction dynamics and scalable manipulation of the mineral ensembles. With this new platform, we devised several mineral-enabled dynamic surfaces and interfaces. For example, we showed that the induced growth of minerals yielded localized inorganic adhesion for biological tissue and reversible focal encapsulation for sensitive components in flexible electronics.